Pneumococcal carriage and otitis media induce salivary antibodies to pneumococcal capsular polysaccharides in children.

@article{Simell2002PneumococcalCA,
  title={Pneumococcal carriage and otitis media induce salivary antibodies to pneumococcal capsular polysaccharides in children.},
  author={Birgit Simell and Terhi M. Kilpi and Helena M. K{\"a}yhty},
  journal={The Journal of infectious diseases},
  year={2002},
  volume={186 8},
  pages={1106-14}
}
Mucosal immunity likely plays an important role in the defense against Streptococcus pneumoniae. This study examined whether pneumococcal carriage and acute otitis media induce mucosal antibodies to pneumococcal capsular polysaccharides (Pnc-PSs) of types 1, 6B, 11A, 14, 19F, and 23F. Immunoglobulin (Ig) A, IgG, and secretory (S) Ig anti-Pnc-PS antibodies were measured by enzyme immunoassay in the saliva of children at ages 6, 12, 18, and 24 months and were analyzed in relation to the previous… CONTINUE READING
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