Pneumococcal Conjugate Vaccines and Otitis Media: An Appraisal of the Clinical Trials

@inproceedings{Fletcher2012PneumococcalCV,
  title={Pneumococcal Conjugate Vaccines and Otitis Media: An Appraisal of the Clinical Trials},
  author={Mark A. Fletcher and Bernard Fritzell},
  booktitle={International journal of otolaryngology},
  year={2012}
}
Streptococcus pneumoniae is the predominant otitis media pathogen and its prevention through effective vaccination could diminish childhood illness and antibiotic use. This paper reviews 5 pneumococcal conjugate vaccine (PCV) trials that used otitis media as an endpoint: Northern California Kaiser Permanente (NCKP; vaccine, 7-valent PCV [PCV7]-CRM); Finnish Otitis Media (FinOM; vaccines, PCV7-CRM or PCV7-OMPC); Native American Trial (vaccine, PCV7-CRM); Pneumococcal Otitis Efficacy Trial (POET… CONTINUE READING

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