Pneumococcal Capsules and Their Types: Past, Present, and Future.

  title={Pneumococcal Capsules and Their Types: Past, Present, and Future.},
  author={Kimball Aaron Geno and Gwendolyn L. Gilbert and Joon Young Song and Ian Chr Skovsted and Keith P. Klugman and Christopher Jones and Helle Bossen Konradsen and Moon H. Nahm},
  journal={Clinical microbiology reviews},
  volume={28 3},
Streptococcus pneumoniae (the pneumococcus) is an important human pathogen. Its virulence is largely due to its polysaccharide capsule, which shields it from the host immune system, and because of this, the capsule has been extensively studied. Studies of the capsule led to the identification of DNA as the genetic material, identification of many different capsular serotypes, and identification of the serotype-specific nature of protection by adaptive immunity. Recent studies have led to the… CONTINUE READING


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