PmPPAF is a pro-phenoloxidase activating factor involved in innate immunity response of the shrimp Penaeus monodon.

@article{Ma2014PmPPAFIA,
  title={PmPPAF is a pro-phenoloxidase activating factor involved in innate immunity response of the shrimp Penaeus monodon.},
  author={Tracy Hoi-Tung Ma and John A. H. Benzie and Jianguo He and Cheng-Bo Sun and Siuming F Chan},
  journal={Developmental and comparative immunology},
  year={2014},
  volume={44 1},
  pages={163-72}
}
One of the major steps in the innate immune response of shrimp includes the activation of serine proteinases of the pro-phenoloxidase pathway by the prophenoloxidase activation enzyme (PPAF). In this study, the cDNA encoding a serine proteinase homologue (SPH) with prophenoloxidase activating activity of Penaeus monodon (PmPPAF) was cloned and characterized. PmPPAF cDNA consists of 1444 nucleotides encoding a protein with 394 amino acid residues. The estimated molecular weight of PmPPAF is 43.5… CONTINUE READING
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  • T.H.T. Ma
  • Developmental and Comparative Immunology
  • 2014
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