Plus-End-Tracking Proteins and Their Interactions at Microtubule Ends

@article{Galjart2010PlusEndTrackingPA,
  title={Plus-End-Tracking Proteins and Their Interactions at Microtubule Ends},
  author={Niels Galjart},
  journal={Current Biology},
  year={2010},
  volume={20},
  pages={R528-R537}
}
Microtubules are cytoskeletal elements that are essential for a large number of intracellular processes, including mitosis, cell differentiation and migration, and vesicle transport. In many cells, the microtubule network is organized in a radial manner, with one end of a microtubule (the minus end) embedded near the nucleus and the other end (the plus end) exploring cytoplasmic space, switching between episodes of growth and shrinkage. Mammalian plus-end-tracking proteins (+TIPs) localize to… CONTINUE READING

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