Pluripotential mesenchymal cells repopulate bone marrow and retain osteogenic properties.

@article{Dahir2000PluripotentialMC,
  title={Pluripotential mesenchymal cells repopulate bone marrow and retain osteogenic properties.},
  author={G A Dahir and Quanjun Cui and Patricia R. Anderson and Christian Simon and C A Joyner and James T. Triffitt and Gary Balian},
  journal={Clinical orthopaedics and related research},
  year={2000},
  volume={379 Suppl},
  pages={S134-45}
}
Precursor cells, isolated from bone marrow, can develop into various cell types and may contribute to skeletal growth, remodeling, and repair. The D1 cell line was cloned from a multipotent mouse bone marrow stromal precursor and has osteogenic, chondrogenic, and adipogenic properties. The osteogenic phenotype of these precursor cells is relevant to the process of fracture healing and osteointegration of prosthetic implants. The D1 cells were labeled genetically using a replication incompetent… CONTINUE READING

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