Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development.

@article{Davis2011PluripotentSC,
  title={Pluripotent stem cell models of cardiac disease and their implication for drug discovery and development.},
  author={Richard P Davis and Cathelijne W. van den Berg and Simona Casini and Stefan R Braam and Christine L Mummery},
  journal={Trends in molecular medicine},
  year={2011},
  volume={17 9},
  pages={475-84}
}
Recent advances in pluripotent stem cell biology now make it possible to generate human cardiomyocytes in vitro from both healthy individuals and from patients with cardiac abnormalities. This offers unprecedented opportunities to study cardiac disease development 'in a dish' and establish novel platforms for drug discovery, either to prevent disease… CONTINUE READING