Pluripotent embryonic stem cells from the rat are capable of producing chimeras.

@article{Iannaccone1994PluripotentES,
  title={Pluripotent embryonic stem cells from the rat are capable of producing chimeras.},
  author={Philip Iannaccone and Greg Taborn and Ray Garton and M D Caplice and David R. Brenin},
  journal={Developmental biology},
  year={1994},
  volume={163 1},
  pages={288-92}
}
Embryonic stem cells have been enormously important in the production of targeted mutations in mice used in the study of gene function and biological aspects of disease states. The use of these cells for mouse studies is now wide-spread but the production of animals from similar cell lines derived from other species has not been previously reported. We demonstrate here the derivation of diploid rat embryonic stem cells (RESC-01). RESC-01 cells are SSEA-1 and alkaline phosphatase positive, grow… CONTINUE READING

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