Pluripotency: Partial reprogramming induces cancer

somatic cell reprogramming to produce induced pluripotent stem cells (iPSCs) results in cells with increased proliferation rates and the ability to self-renew, similar to the generation of cancer cells from somatic cells. Therefore, Ohnishi, Semi et al. investigated whether iPSC generation has any similarities with tumorigenesis. iPSCs can be generated from… CONTINUE READING