Plexin: A novel neuronal cell surface molecule that mediates cell adhesion via a homophilic binding mechanism in the presence of calcium ions

@article{Ohta1995PlexinAN,
  title={Plexin: A novel neuronal cell surface molecule that mediates cell adhesion via a homophilic binding mechanism in the presence of calcium ions},
  author={Kunimasa Ohta and Akihito Mizutani and Atsushi Kawakami and Yasunori Murakami and Yasuyo Kasuya and Shin Takagi and Hideaki Tanaka and Hajime Fujisawa},
  journal={Neuron},
  year={1995},
  volume={14},
  pages={1189-1199}
}
Plexin (previously referred to as B2) is a neuronal cell surface molecule that has been identified in Xenopus. cDNA cloning reveals that plexin has no homology to known neuronal cell surface molecules but possesses, in its extracellular segment, three internal repeats of cysteine clusters that are homologous to the cysteine-rich domain of the c-met proto-oncogene protein product. The exogenous plexin proteins expressed on the surfaces of L cells by cDNA transfection mediate cell adhesion via a… CONTINUE READING

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