Pleurisy in primary Sjögren's syndrome: T cell receptor beta-chain variable region gene bias and local autoantibody production in the pleural effusion.

@article{Kawamata1997PleurisyIP,
  title={Pleurisy in primary Sj{\"o}gren's syndrome: T cell receptor beta-chain variable region gene bias and local autoantibody production in the pleural effusion.},
  author={Kiyoshi Kawamata and Hitomi Haraoka and Shunsei Hirohata and Toko Hashimoto and Robert N. Jenkins and Peter E Lipsky},
  journal={Clinical and experimental rheumatology},
  year={1997},
  volume={15 2},
  pages={193-6}
}
Pleurisy with or without effusion has not been considered to be associated with primary Sjögren's syndrome (SS), but rather to represent a manifestation of the underlying disorder, usually rheumatoid arthritis in secondary SS. We describe a patient with primary SS who presented with pleural effusions (PE) as an initial manifestation. Serological studies of paired serum and PE specimens demonstrated the occurrence of local immune reactions in the pleura, including the production of rheumatoid… CONTINUE READING