Pleomorphic dermal neoplasms: a review.

@article{Brenn2014PleomorphicDN,
  title={Pleomorphic dermal neoplasms: a review.},
  author={Thomas Brenn},
  journal={Advances in anatomic pathology},
  year={2014},
  volume={21 2},
  pages={
          108-30
        }
}
Pleomorphic neoplasms are typically associated with high-grade malignant behavior, but this does not readily apply to primary cutaneous tumors. Despite morphologic features suggestive of malignancy, atypical fibroxanthoma, the classic example of a pleomorphic dermal neoplasm, is characterized by indolent clinical behavior. Atypical fibroxanthoma is a distinctive clinicopathologic disease affecting sun-damaged skin of elderly males. Histologically, it is often ulcerated and dermal based with… CONTINUE READING

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