Pleiotropic hierarchies from high-dimensional phenotyping by RNA interference

@inproceedings{Markowetz2006PleiotropicHF,
  title={Pleiotropic hierarchies from high-dimensional phenotyping by RNA interference},
  author={Florian Markowetz and Juby Jacob and Stefan Bentink and Rainer Spang},
  year={2006}
}
RNA interference (RNAi) is the targeted silencing of gene expression by small interfering RNAs. As an experimental technique it can be applied on a genome-wide scale to probe gene function. Data from large-scale RNAi screens are available for model organisms like C. elegans and Drosophila melanogaster. For many genes silencing leads to a number of distinct… CONTINUE READING