Pleiotropic and epistatic behavior of a ring-hydroxylating oxygenase system in the polycyclic aromatic hydrocarbon metabolic network from Mycobacterium vanbaalenii PYR-1.

Abstract

Despite the considerable knowledge of bacterial high-molecular-weight (HMW) polycyclic aromatic hydrocarbon (PAH) metabolism, the key enzyme(s) and its pleiotropic and epistatic behavior(s) responsible for low-molecular-weight (LMW) PAHs in HMW PAH-metabolic networks remain poorly understood. In this study, a phenotype-based strategy, coupled with a spray… (More)
DOI: 10.1128/JB.01945-14

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@article{Kweon2014PleiotropicAE, title={Pleiotropic and epistatic behavior of a ring-hydroxylating oxygenase system in the polycyclic aromatic hydrocarbon metabolic network from Mycobacterium vanbaalenii PYR-1.}, author={Ohgew Kweon and Seong-Jae Kim and Dae-Wi Kim and Jeong Myeong Kim and Hyun-lee Kim and Youngbeom Ahn and John B. Sutherland and Carl Cerniglia}, journal={Journal of bacteriology}, year={2014}, volume={196 19}, pages={3503-15} }