Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs

@article{Rado2017PleiotropicAI,
  title={Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs},
  author={Santiago Rad{\'i}o and S. Fontenla and V. Solana and Anna C. Matos Salim and F. Ara{\'u}jo and Pedro Ortiz and C. Hob{\'a}n and E. Miranda and V. Gayo and F. S. Pais and H. Solana and Guilherme Oliveira and P. Smircich and J. Tort},
  journal={Parasites & Vectors},
  year={2017},
  volume={11}
}
  • Santiago Radío, S. Fontenla, +11 authors J. Tort
  • Published 2017
  • Biology, Medicine
  • Parasites & Vectors
  • BackgroundFasciola hepatica is the main agent of fasciolosis, a zoonotic disease affecting livestock worldwide, and an emerging food-borne disease in humans. Even when effective treatments are available, drugs are costly and can result in tolerance, liver damage and normally they do not prevent reinfection. Drug-resistant strains in livestock have been reported in various countries and, more worryingly, drug resistance in human cases has emerged in South America. The present study aims to… CONTINUE READING
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