Pleiotropic Effects of Statins

@article{Pedersen2010PleiotropicEO,
  title={Pleiotropic Effects of Statins},
  author={T. Pedersen},
  journal={American Journal of Cardiovascular Drugs},
  year={2010},
  volume={10},
  pages={10-17}
}
  • T. Pedersen
  • Published 2010
  • Medicine
  • American Journal of Cardiovascular Drugs
Abstract3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) are extremely effective at reducing low-density lipoprotein (LDL) cholesterol and have been demonstrated to reduce mortality and the risk of major cardiovascular events in a number of large primary and secondary prevention studies. The linear relationship between LDL-cholesterol and cardiovascular risk suggests statins work solely by reducing LDL-cholesterol, and that ancillary properties do not contribute to… Expand
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