Pleiotropic Effects of Deubiquitinating Enzyme Ubp5 on Growth and Pathogenesis of Cryptococcus neoformans

@inproceedings{Fang2012PleiotropicEO,
  title={Pleiotropic Effects of Deubiquitinating Enzyme Ubp5 on Growth and Pathogenesis of Cryptococcus neoformans},
  author={W. J. Fang and Michael S. Price and Dena L. Toffaletti and Jennifer L. Tenor and Marisol Betancourt-Quiroz and Jennifer L. Price and Weihua Pan and Wan-Qing Liao and John R Perfect},
  booktitle={PloS one},
  year={2012}
}
Ubiquitination is a reversible protein modification that influences various cellular processes in eukaryotic cells. Deubiquitinating enzymes remove ubiquitin, maintain ubiquitin homeostasis and regulate protein degradation via the ubiquitination pathway. Cryptococcus neoformans is an important basidiomycete pathogen that causes life-threatening meningoencephalitis primarily in the immunocompromised population. In order to understand the possible influence deubiquitinases have on growth and… CONTINUE READING

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