Pleiotropic Compensation in the Regulation of Extracellular Protein Formation by a Low a - Toxin - producing Variant of Staphylococcus aureus

  • G E O F F R E Y C O L E M A N
  • Published 1981

Abstract

The changes in bacterial density, total extracellular protein and haemolysin produced by bacteria from overnight cultures of Staphylococcus aureus (Wood 46) and a low a-toxin-producing variant suspended in fresh medium were followed at 37 OC. Although five extracellular proteins were produced at a reduced level by the variant (a-toxin formation was reduced more than tenfold), the differential rates of total extracellular protein formation by the two organisms were identical. The results are consistent with a common regulatory mechanism for extracellular protein formation in which a pleiotropic compensation may occur in order to saturate the extracellular protein-producing capability.

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@inproceedings{N1981PleiotropicCI, title={Pleiotropic Compensation in the Regulation of Extracellular Protein Formation by a Low a - Toxin - producing Variant of Staphylococcus aureus}, author={G E O F F R E Y C O L E M A N}, year={1981} }