Pleiotropic Actions of Forskolin Result in Phosphatidylserine Exposure in Primary Trophoblasts

@inproceedings{Riddell2013PleiotropicAO,
  title={Pleiotropic Actions of Forskolin Result in Phosphatidylserine Exposure in Primary Trophoblasts},
  author={Meghan R. Riddell and Bonnie Winkler-Lowen and Yanyan Jiang and Sandra T Davidge and Larry J. Guilbert},
  booktitle={PloS one},
  year={2013}
}
Forskolin is an extract of the Coleus forskholii plant that is widely used in cell physiology to raise intracellular cAMP levels. In the field of trophoblast biology, forskolin is one of the primary treatments used to induce trophoblastic cellular fusion. The syncytiotrophoblast (ST) is a continuous multinucleated cell in the human placenta that separates maternal from fetal circulations and can only expand by fusion with its stem cell, the cytotrophoblast (CT). Functional investigation of any… CONTINUE READING
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