Pleasure rather than salience activates human nucleus accumbens and medial prefrontal cortex.

  title={Pleasure rather than salience activates human nucleus accumbens and medial prefrontal cortex.},
  author={Dean Sabatinelli and Margaret M. Bradley and Peter J. Lang and Vincent D Costa and Francesco Versace},
  journal={Journal of neurophysiology},
  volume={98 3},
Recent human functional imaging studies have linked the processing of pleasant visual stimuli to activity in mesolimbic reward structures. However, whether the activation is driven specifically by the pleasantness of the stimulus, or by its salience, is unresolved. Here we find in two studies that free viewing of pleasant images of erotic and romantic couples prompts clear, reliable increases in nucleus accumbens (NAc) and medial prefrontal cortex (mPFC) activity, whereas equally arousing… 

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