Playing for half the deck: the molecular biology of meiosis.

@article{Champion2002PlayingFH,
  title={Playing for half the deck: the molecular biology of meiosis.},
  author={Mia D. Champion and R. Scott Hawley},
  journal={Nature cell biology},
  year={2002},
  volume={4 Suppl},
  pages={s50-6}
}
Meiosis reduces the number of chromosomes carried by a diploid organism by half, partitioning precisely one haploid genome into each gamete. The basic events of meiosis reflect three meiosis-specific processes: first, pairing and synapsis of homologous chromosomes; second, high-frequency, precisely controlled, reciprocal crossover; third, the regulation of sister-chromatid cohesion (SCC), such that during anaphase I, SCC is released along the chromosome arms, but not at the centromeres. The… CONTINUE READING

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