Platycarya strobilacea S. et Z. Extract Has a High Antioxidant Capacity and Exhibits Hair Growth-promoting Effects in Male C57BL/6 Mice

  title={Platycarya strobilacea S. et Z. Extract Has a High Antioxidant Capacity and Exhibits Hair Growth-promoting Effects in Male C57BL/6 Mice},
  author={Eun Jin Kim and Joo‐Yeon Choi and Byung Cheol Park and Bog Hieu Lee},
  journal={Preventive Nutrition and Food Science},
  pages={136 - 144}
This study was conducted to evaluate the effects of Platycarya strobilacea S. et Z. (PSE) extract on mouse hair growth and to determine the mechanism of action of PSE. PSE was purchased and its antioxidant activities, such as electron donating ability, total polyphenol content, and flavonoid content were tested. Toxicity during topical treatment was determined by the CCK-8 assay, a cell viability test. Fifteen 4-week-old male C57BL/6 mice were assigned to receive one of three treatments… 

Figures and Tables from this paper

Effect of Miscanthus sinensis var. purpurascens Flower Extract on Proliferation and Molecular Regulation in Human Dermal Papilla Cells and Stressed C57BL/6 Mice

The MSP flower extract may have hair growth-promotion activities and showed the earlier transition of hair follicles from the telogen to the anagen phase in mice treated with MSP.

Hair Growth Promotion Effect of Nelumbinis Semen Extract with High Antioxidant Activity

This study investigated the hair regeneration promotion and hair loss prevention properties of Nelumbinis Semen (NS) extract in vitro and in vivo. The effect of NS on the proliferation and migration

Action Mechanism of Natural Plant Extracts for Hair Loss Prevention and Hair Growth Promotion in C57BL/6 Mice

The result suggests that NPE promotes hair growth while inducing anagen hair growth in animals through genetic regulation while, simultaneously preventing hair loss.

Efficacy of topical tofacitinib in promoting hair growth in non-scarring alopecia: possible mechanism via VEGF induction

Topical tofacitinib is effective in promoting hair growth, and the possible mechanism involves increased VEGF levels and lowered inflammation.

Platycarya strobilacea leaf extract protects mice brain with focal cerebral ischemia by antioxidative property

It is suggested that PSL can exert protective effects against fCI, and the mechanism may involve HO-1 upregulation, an antioxidant enzyme in the lesion area.

Phytotherapeutic Interventions using Rodent Models of Hair Loss: Current Research and Future Strategy

Hair follicles are special additions to mammalian skin with intricate differentiation and growth characteristics. They constantly undergo cycles of regression and regeneration throughout the lifespan

Fisetin Promotes Hair Growth by Augmenting TERT Expression

Results suggest that resveratrol and fisetin induce a shift from telogen to anagen in the hair follicles by inducing proliferation of hair follicle bulge stem cells, thus promoting hair growth.

Review of Hair Follicle Dermal Papilla cells as in vitro screening model for hair growth

The pivotal role of DPCs in the forefront of hair research as screening platforms is highlighted by providing insights into mechanistic action at cellular level, which may further direct the development of novel hair growth modulators.



Hair Growth Promotion Effect of a Bio-Active Shampoo, Bonogen in C57BL/6 Mice

The results suggest that bonogen shampoo has hair growth promoting activities and may be useful for treatment of bald or alopecia.

Promotion Effect of Black Sesame Oil on Hair Growth in an Alopecia Model of C57BL/6 Mice

The results indicate that black sesame oil effectively stimulated hair growth in an animal model via several mechanisms and that it can be used practically for hair growth or prevention of hair loss in human beings.

The Preclinical and Clinical Effects of Herbal Product Containing Rosa mutiflora Roots Extracts as a Main Component on the Hair Growth Promotion

RMHP have hair loss prevention effect and hair growth promotion effect to hair loss patients and was observed to significantly stimulate hair growth against 80% negative con-trol group.

Human hair growth enhancement in vitro by green tea epigallocatechin-3-gallate (EGCG).

The hair growth promoting effect of Sophora flavescens extract and its molecular regulation.

The effects of tea polyphenolic compounds on hair loss among rodents.

The results showed that 33% of the mice in experimental Group A, who received polyphenol extract in their drinking water, had significant hair regrowth during six months of treatment (p = 0.014).

Yam (Dioscorea batatas) Root and Bark Extracts Stimulate Osteoblast Mineralization by Increasing Ca and P Accumulation and Alkaline Phosphatase Activity

It is suggested that both yam root and bark extracts stimulate osteogenic function in osteoblasts by stimulating bone matrix maturation by increasing collagen synthesis, ALP activity, and matrix mineralization.

Anti-adipogenic and Pro-osteoblastogenic Activities of Spergularia marina Extract

S. marina could be a source of functional food ingredients that improve osteoporosis and obesity and elucidate the mechanism of action and active ingredients of S. marinas, which would provide researchers with a better understanding of the nutraceutical and therapeutic applications of Spergularia marina.

The Stimulation of Phenolics and Antioxidant Activity in Pea (Pisum sativum) Elicited by Genetically Transformed Anise Root Extract

G6PDH specific activity, the first committed step of the pentose phosphate pathway, was negatively associated with shoot growth and proline concentrations, and antioxidant protection factor in pea shoots was also stimulated by AR-10 extracts.

Induction of anagen in telogen mouse skin by topical application of FK506, a potent immunosuppressant.

Results clearly demonstrate that topical application of FK506 induces anagen hair growth in telogen mouse skin and indicate that the hair-growth-stimulating effect of Fk506 is due at least in part to its promoting effect on the hair cycle.