Platinum-induced hearing loss after treatment for childhood cancer.

  title={Platinum-induced hearing loss after treatment for childhood cancer.},
  author={Jorrit W van As and H. van den Berg and E. C. van Dalen},
  journal={The Cochrane database of systematic reviews},
  • Jorrit W van As, H. van den Berg, E. C. van Dalen
  • Published 2016
  • Medicine
  • The Cochrane database of systematic reviews
  • BACKGROUND Platinum-based therapy, including cisplatin, carboplatin, oxaliplatin or a combination of these, is used to treat a variety of paediatric malignancies. Unfortunately, one of the most important adverse effects is the occurrence of hearing loss or ototoxicity. There is a wide variation in the reported prevalence of platinum-induced ototoxicity and the associated risk factors. More insight into the prevalence of and risk factors for platinum-induced hearing loss is essential in order to… CONTINUE READING
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