Platform influence on DNA microarray data in postmortem brain research

@article{Hollingshead2005PlatformIO,
  title={Platform influence on DNA microarray data in postmortem brain research},
  author={Deborah Hollingshead and David Andrew Lewis and K{\'a}roly Mirnics},
  journal={Neurobiology of Disease},
  year={2005},
  volume={18},
  pages={649-655}
}
In addition to the substantial biological diversity among humans, our limited ability to reliably measure expression changes of small magnitude significantly reduces our capacity to obtain convergent sets of transcriptome data in postmortem brain. In particular, differences in the structure and sensitivity/reproducibility of microarray platforms, and in the variety of tools used to analyze microarray data, strongly influence experimental outcome. In order to better understand the sensitivity… CONTINUE READING

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