Platelets and viruses: an ambivalent relationship

@article{Flaujac2009PlateletsAV,
  title={Platelets and viruses: an ambivalent relationship},
  author={Claire Flaujac and Siham Boukour and Elisabeth M Cramer-Bord{\'e}},
  journal={Cellular and Molecular Life Sciences},
  year={2009},
  volume={67},
  pages={545-556}
}
Thrombocytopenia is a frequent complication of viral infections providing evidence that interaction of platelets with viruses is an important pathophysiological phenomenon. Multiple mechanisms are involved depending on the nature of the viruses involved. These include immunological platelet destruction, inappropriate platelet activation and consumption, and impaired megakaryopoiesis. Viruses bind platelets through specific receptors and identified ligands, which lead to mutual alterations of… CONTINUE READING

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These include immunological platelet destruction , inappropriate platelet activation and consumption , and impaired megakaryopoiesis .
This review also shows that more work is still needed to precisely identify platelet roles in viral infections , and to answer the challenge of viral safety in platelet transfusion .
Thrombocytopenia is a frequent complication of viral infections providing evidence that interaction of platelets with viruses is an important pathophysiological phenomenon .
This review also shows that more work is still needed to precisely identify platelet roles in viral infections , and to answer the challenge of viral safety in platelet transfusion .
These include immunological platelet destruction , inappropriate platelet activation and consumption , and impaired megakaryopoiesis .
This review also shows that more work is still needed to precisely identify platelet roles in viral infections , and to answer the challenge of viral safety in platelet transfusion .
Thrombocytopenia is a frequent complication of viral infections providing evidence that interaction of platelets with viruses is an important pathophysiological phenomenon .
This review also shows that more work is still needed to precisely identify platelet roles in viral infections , and to answer the challenge of viral safety in platelet transfusion .
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