Platelets and their microparticles as key players in pathophysiological responses.

@article{Varon2015PlateletsAT,
  title={Platelets and their microparticles as key players in pathophysiological responses.},
  author={David Varon and Ela Shai},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2015},
  volume={13 Suppl 1},
  pages={S40-6}
}
Platelets are known to play a central role in primary hemostasis as well as in the pathophysiology of thrombotic disorders. However, in addition to hemostasis, platelets are involved in a variety of pathophysiological responses including immune responses, inflammation, angiogenesis, tissue regeneration, and cancer metastasis. Recent studies revealed a significant role for platelet-derived microparticles (PMP), in these responses. PMP communicate with, and deliver signals to, other cells, induce… CONTINUE READING