Platelets and Neutrophils from Healthy Term Neonates Exhibit Increased Levels of Immunoglobulins

@article{Silliman1995PlateletsAN,
  title={Platelets and Neutrophils from Healthy Term Neonates Exhibit Increased Levels of Immunoglobulins},
  author={Christopher C. Silliman and Nancy A Cusack and Nancy J Swanson and Simin Ghaffarifar and Daniel R. Ambruso},
  journal={Pediatric Research},
  year={1995},
  volume={38},
  pages={993-997}
}
ABSTRACT: Immune-mediated thrombocytopenia and neutropenia are not uncommon problems in the newborn period. Such cytopenias have been associated with increased levels of IgG, IgM, or both, in the serum, documented by indirect assay, and/or on the cell surface, documented by direct assay, and decreased cell survival. However, interpretation of measurement of platelet- or neutrophil-associated antibodies is problematic due to the lack of data from healthy neonates. In this study, both direct and… CONTINUE READING