Platelets alter tumor cell attributes to propel metastasis: programming in transit.


Metastasis of epithelial tumors critically depends on acquisition of a disseminating phenotype that allows tumor cells to colonize distant organs. In this issue of Cancer Cell, Labelle et al. demonstrate that an epithelial-mesenchymal-like transition can be induced by interaction between platelets and tumor cells. 
DOI: 10.1016/j.ccr.2011.11.001

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