Platelet transfusion: a systematic review of the clinical evidence.

@article{Kumar2015PlateletTA,
  title={Platelet transfusion: a systematic review of the clinical evidence.},
  author={Ambuj Kumar and Rahul D Mhaskar and B J Grossman and Richard Max Kaufman and Aaron A R Tobian and Steven H. Kleinman and Terry Gernsheimer and Alan T. Tinmouth and Benjamin Djulbegovic},
  journal={Transfusion},
  year={2015},
  volume={55 5},
  pages={
          1116-27; quiz 1115
        }
}
BACKGROUND Platelet (PLT) transfusion is indicated either prophylactically or therapeutically to reduce the risk of bleeding or to control active bleeding. Significant uncertainty exists regarding the appropriate use of PLT transfusion and the optimal threshold for transfusion in various settings. We formulated 12 key questions to assess the role of PLT transfusion. STUDY DESIGN AND METHODS We performed a systematic review (SR) of randomized controlled trials (RCTs) and observational studies… CONTINUE READING
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