Platelet surface collagen receptor polymorphisms: variable receptor expression and thrombotic/hemorrhagic risk.


TWO ARTICLES in this issue focus attention on the a2b1 integrin, a platelet surface collagen receptor. The articles address the potential contributions of varying a2b1 integrin expression to the manifestation of hemorrhagic or thrombotic disease. For some years, fibrillar collagens have been recognized as the most thrombogenic macromolecular constituents of… (More)