Platelet serotonin uptake sites increased in drinkers ofayahuasca

@article{Callaway2005PlateletSU,
  title={Platelet serotonin uptake sites increased in drinkers ofayahuasca},
  author={James C. Callaway and Mauno M. Airaksinen and Dennis J. Mckenna and Glacus S. Brito and Charles S. Grob},
  journal={Psychopharmacology},
  year={2005},
  volume={116},
  pages={385-387}
}
The binding of [3H]citalopram to the platelet 5-hydroxytryptamine (5-HT) transporter was measured in a group of healthy male drinkers ofayahuasca, a psychoactive sacrament indigenous to Amazonia, and a group healthy male controls. An increased number of binding sites (Bmax) in the platelets of ayahuasca drinkers was found, while the dissociation constant (Kd) remained the same for both groups. If indicative of neuronal 5-HT uptake activity, these results would suggest a decreased concentration… Expand
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