Platelet serotonin uptake during myocardial ischemia.

  title={Platelet serotonin uptake during myocardial ischemia.},
  author={H H Oei and W E Hughes and Stephen W. Schaffer and Gesina L. Longenecker and Thomas M. Glenn},
  journal={American heart journal},
  volume={106 5 Pt 1},
Platelets are believed to play a role in the pathologic sequelae of acute myocardial ischemia. Several of the compounds generated and released by activated platelets during cardiac ischemia may contribute to the production of cellular necrosis (free oxygen radicals), coronary vasoconstriction (thromboxane, serotonin, catecholamines), and perpetuation of the platelet aggregatory reaction (thromboxane, serotonin, adenosine diphosphate). In the present study, it was demonstrated that platelet… CONTINUE READING