Platelet secretory behaviour: as diverse as the granules … or not?

@article{Heijnen2015PlateletSB,
  title={Platelet secretory behaviour: as diverse as the granules … or not?},
  author={Harry F Heijnen and Peter van der Sluijs},
  journal={Journal of thrombosis and haemostasis : JTH},
  year={2015},
  volume={13 12},
  pages={2141-51}
}
Platelets play a central role in the arrest of bleeding after damage to a blood vessel and in the development of thrombosis. Platelets rapidly respond after interaction with sub-endothelial components and release cargo from their storage granules. The three principal granule types of platelets are α-granules, dense granules and lysosomes. Timed release of granule contents and regulated expression of critical receptors are essential for maintenance of the platelet thrombus, yet also have… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Platelets, circulating tumor cells, and the circulome

Cancer and Metastasis Reviews • 2017
View 4 Excerpts
Highly Influenced

Platelet Interaction with Innate Immune Cells.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie • 2016

References

Publications referenced by this paper.
Showing 1-10 of 103 references

Yeast homologues of tomosyn and lethal giant larvae function in exocytosis © 2015 International Society on Thrombosis and Haemostasis

K Lehman, G Rossi, JE Adamo, P. Brennwald
2015

Platelets guide the formation of early metastatic niches.

Proceedings of the National Academy of Sciences of the United States of America • 2014

Similar Papers

Loading similar papers…