Platelet secretory behaviour: as diverse as the granules … or not?

  title={Platelet secretory behaviour: as diverse as the granules … or not?},
  author={Harry F Heijnen and Peter van der Sluijs},
  journal={Journal of thrombosis and haemostasis : JTH},
  volume={13 12},
Platelets play a central role in the arrest of bleeding after damage to a blood vessel and in the development of thrombosis. Platelets rapidly respond after interaction with sub-endothelial components and release cargo from their storage granules. The three principal granule types of platelets are α-granules, dense granules and lysosomes. Timed release of granule contents and regulated expression of critical receptors are essential for maintenance of the platelet thrombus, yet also have… CONTINUE READING
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