Platelet mitochondrial activity and pesticide exposure in early Parkinson's disease.

@article{Bronstein2015PlateletMA,
  title={Platelet mitochondrial activity and pesticide exposure in early Parkinson's disease.},
  author={Jeff M. Bronstein and Kimberly C. Paul and Laurice Yang and Richard H. Haas and Clifford W. Shults and Thuy P. Le and Beate R. Ritz},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2015},
  volume={30 6},
  pages={862-6}
}
BACKGROUND Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson's disease (PD), but the cause of this dysfunction is unclear. METHODS Platelet mitochondrial complex I and I/III (nicotinamide adenine dinucleotide cytochrome c reductase, NCCR) activities were measured in early PD patients and matched controls enrolled in a population-based case-control study. Ambient agricultural pesticide exposures were assessed with a geographic information system and California… CONTINUE READING