Platelet microparticle-mediated transfer of miR-939 to epithelial ovarian cancer cells promotes epithelial to mesenchymal transition

@inproceedings{Tang2017PlateletMT,
  title={Platelet microparticle-mediated transfer of miR-939 to epithelial ovarian cancer cells promotes epithelial to mesenchymal transition},
  author={Meiling Tang and Lu Jiang and Yingying Lin and Xiaoli Wu and Kai Wang and Qizhi He and Xipeng Wang and Weiping Li},
  booktitle={Oncotarget},
  year={2017}
}
Epithelial ovarian cancer (EOC) patients frequently suffer from thrombocytosis, which leads to a poor prognosis. However, the mechanism underlying platelet regulation of biological behavior in EOC remains unclear. The associations between clinicopathological characteristics and thrombocytosis in 171 EOC patients were studied, preoperative thrombocytosis was significantly associated with the stage, metastasis scope, level of preoperative CA125 and overall survival. When SKOV3 cells were… CONTINUE READING

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