Platelet membrane and calcium control abnormalities in essential hypertension.

  title={Platelet membrane and calcium control abnormalities in essential hypertension.},
  author={Fritz R. B{\"u}hler and Th{\'e}rese J. Resink},
  journal={American journal of hypertension},
  volume={1 1},
The mechanisms whereby intracellular calcium concentration is controlled are briefly reviewed. With the current knowledge of both calcium homeostasis and the function and properties of cellular Ca2+-target proteins/signal transduction systems, a dysfunction of cellular calcium metabolism is considered in relation to the pathogenesis of hypertension. Although the enhanced peripheral vascular resistance characteristic of hypertension is ultimately a function of Ca2+ availability for smooth muscle… CONTINUE READING
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