Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass.

@article{Rinder1994PlateletleukocyteAA,
  title={Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass.},
  author={Christine Stowe Rinder and Dezső Ga{\'a}l and L A Student and Brian Richard Smith},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={1994},
  volume={107 1},
  pages={280-8}
}
Cardiopulmonary bypass has been shown in adults to activate platelets and leukocytes, lead to the formation of circulating platelet-leukocyte conjugates, and alter adhesive receptors on both cell types. Pediatric patients with congenital heart disease undergoing cardiopulmonary bypass, however, have not been extensively studied and may represent a group at particular clinical risk for bleeding and pulmonary dysfunction. We studied 13 patients with congenital heart disease undergoing operations… CONTINUE READING

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