Platelet glycoprotein VI.

  title={Platelet glycoprotein VI.},
  author={Stephanie M Jung and Masaaki Moroi},
  journal={Advances in experimental medicine and biology},
Glycoprotein VI (GPVI) is a membrane glycoprotein unique to platelets and has been identified as a physiological receptor for collagen. Damage to a vessel wall exposes the subendothelial component collagen to platelets in the blood flow. Interaction of platelets with collagen via the receptor GPVI results in platelet activation and adhesion--the processes that are essential for thrombus formation. On the platelet surface, GPVI is present as a complex with the homodimeric Fc receptor y-chain… CONTINUE READING


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