Platelet functions in recombinant hirudin-anticoagulated blood.

@article{Glusa1990PlateletFI,
  title={Platelet functions in recombinant hirudin-anticoagulated blood.},
  author={Erika Glusa and Fritz Markwardt},
  journal={Haemostasis},
  year={1990},
  volume={20 2},
  pages={112-8}
}
The influence of genetically engineered recombinant hirudin (r-hirudin) on platelet functions was studied. Depending on the concentration, r-hirudin inhibits the thrombin-induced aggregation and 14C-serotonin secretion to the same extent as native hirudin. Comparative studies in blood anticoagulated by r-hirudin, heparin or citrate show a significantly… CONTINUE READING