Platelet function testing in hirudin and BAPA anticoagulated blood.

  title={Platelet function testing in hirudin and BAPA anticoagulated blood.},
  author={Helen Mani and Mirna Hellis and Edelgard Lindhoff-Last},
  journal={Clinical chemistry and laboratory medicine},
  volume={49 3},
BACKGROUND Sodium citrate is the most commonly used anticoagulant for platelet function testing. However, the use of citrated blood for platelet function analysis has been criticized due to creation of a non-physiological milieu. Moreover, platelet function measurements performed with citrated blood need to be completed within 4 h after blood collection. Alternatively, hirudin and recently, a dual thrombin/factor Xa inhibitor benzylsulfonyl-D-Arg-Pro-4-amidinobenzylamide (BAPA), can be used to… CONTINUE READING