Platelet function profiles in the elderly: results of a pharmacodynamic study in patients on clopidogrel therapy and effects of switching to prasugrel 5 mg in patients with high platelet reactivity.

@article{Capranzano2011PlateletFP,
  title={Platelet function profiles in the elderly: results of a pharmacodynamic study in patients on clopidogrel therapy and effects of switching to prasugrel 5 mg in patients with high platelet reactivity.},
  author={Piera Capranzano and Claudia Ina Tamburino and Davide Capodanno and Eligio Miccich{\`e} and Lucia V D'Urso and Valeria Calvi and Dominick Joseph Angiolillo and Corrado Tamburino},
  journal={Thrombosis and haemostasis},
  year={2011},
  volume={106 6},
  pages={1149-57}
}
Studies specifically designed to assess clopidogrel response in the elderly as well as treatment alternatives to improve platelet inhibition in this high-risk population are lacking. This study aimed to define pharmacodynamic (PD) profiles, including high platelet reactivity (HPR) rates, among elderly patients on maintenance clopidogrel therapy and to… CONTINUE READING