Platelet function in pre-eclampsia.

  title={Platelet function in pre-eclampsia.},
  author={Rashid Saeed Kazmi and Alan Cooper and Bashir A Lwaleed},
  journal={Seminars in thrombosis and hemostasis},
  volume={37 2},
Pronounced hemostatic changes occur during pregnancy, and the balance shifts markedly in favor of hypercoagulability. Although primarily a result of a marked rise in the levels of several procoagulants and a fall in some natural anticoagulants, platelet activation also contributes to this prothrombotic tendency. Several studies have confirmed the accentuation of platelet activation in pre-eclampsia (P-EC), which remains an important obstetric complication affecting ~2 to 4% of pregnancies… CONTINUE READING