Platelet dynamics following allergen challenge in allergic asthmatics.

  title={Platelet dynamics following allergen challenge in allergic asthmatics.},
  author={Paul J. Sullivan and Z H Jafar and P L Harbinson and Louise J. Restrick and John F. Costello and Clive P Page},
  journal={Respiration; international review of thoracic diseases},
  volume={67 5},
BACKGROUND There is evidence that platelet activation occurs in allergic inflammation and asthma, but little is known about the role platelets play in airway inflammation associated with asthma. OBJECTIVES In the present study, we have investigated the kinetics of platelet activation following allergen provocation of allergic asthmatics to determine the dynamics of platelet activation relative to changes in lung function and changes in airway inflammation. METHODS Changes in platelet count… CONTINUE READING
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