Platelet-derived growth factors induced lymphangiogenesis: evidence, unanswered questions and upcoming challenges

@inproceedings{Jitariu2015PlateletderivedGF,
  title={Platelet-derived growth factors induced lymphangiogenesis: evidence, unanswered questions and upcoming challenges},
  author={Andreea Adriana Jitariu and Anca Maria C{\^i}mpean and Nilima Rajpal Kundnani and Marius Raica},
  booktitle={Archives of medical science : AMS},
  year={2015}
}
Crosstalk between angiogenesis and lymphangiogenesis in embryonic development continues during postnatal life and has specific mechanisms involving factors that initiate activation of the intracellular cascade for their specific receptors. Platelet-derived growth factors (PDGFs) and their corresponding receptors (PDGFRs) are known as important regulators of blood vessel development in both normal and pathologic angiogenesis. Despite some recent papers which reported a potential role of the PDGF… CONTINUE READING

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