Platelet-derived growth factors for GMP-compliant propagation of mesenchymal stromal cells.

@article{Schallmoser2009PlateletderivedGF,
  title={Platelet-derived growth factors for GMP-compliant propagation of mesenchymal stromal cells.},
  author={Katharina Schallmoser and Eva Rohde and Christina Bartmann and Anna Christina Obenauf and Andreas Reinisch and Dirk Strunk},
  journal={Bio-medical materials and engineering},
  year={2009},
  volume={19 4-5},
  pages={271-6}
}
Stem cell-based therapies are a promising prospect for regenerative medicine. Particularly, human multipotent mesenchymal stromal cells (MSCs) are currently in focus regarding their regenerative and immune modulating capacities. An increasing number of clinical trials investigating MSC efficiency and safety are ongoing. Ex vivo propagation of human MSCs is considered to be a prerequisite for MSC therapy. The to date standard use of fetal bovine serum in cell culture bears risks including… CONTINUE READING