Platelet derived growth factor releasing chitosan sponge for periodontal bone regeneration.

@article{Park2000PlateletDG,
  title={Platelet derived growth factor releasing chitosan sponge for periodontal bone regeneration.},
  author={Yoon Jeong Park and Young Moo Lee and Sue Nie Park and Shiowshuh Sheen and Chong Pyoung Chung and Seung Jin Lee},
  journal={Biomaterials},
  year={2000},
  volume={21 2},
  pages={153-9}
}
With an aim of improving bone regeneration, chitosan sponge containing platelet-derived growth factor-BB (PDGF-BB) were developed. For fabrication of chitosan sponge, chitosan solution was freeze-dried, crosslinked and freeze-dried again. PDGF-BB was incorporated into the chitosan sponge by soaking chitosan sponge into the PDGF-BB solution. Release kinetics of PDGF-BB, cell attachment, proliferation capacity and bony regenerative potentials of PDGF-BB-loaded chitosan sponge were investigated… CONTINUE READING