Platelet-derived growth factor modulates the primordial to primary follicle transition.

@article{Nilsson2006PlateletderivedGF,
  title={Platelet-derived growth factor modulates the primordial to primary follicle transition.},
  author={Eric E Nilsson and Chris Detzel and Michael K. Skinner},
  journal={Reproduction},
  year={2006},
  volume={131 6},
  pages={1007-15}
}
Primordial follicles steadily leave the arrested pool and undergo a primordial to primary follicle transition during the female reproductive lifespan. When the available pool of primordial follicles is depleted reproduction ceases and humans enter menopause. The present study was designed to investigate the actions of several growth factors previously identified as candidate regulatory factors for the primordial to primary follicle transition with a microarray analysis. Ovaries from 4-day-old… CONTINUE READING
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