Platelet-derived growth factor gene polymorphism in recurrent hepatitis C infection after liver transplantation.

@article{BenAri2006PlateletderivedGF,
  title={Platelet-derived growth factor gene polymorphism in recurrent hepatitis C infection after liver transplantation.},
  author={Ziv Z Ben-Ari and Anat R. Tambur and Orit Pappo and Jaqueline Sulkes and Vera Pravica and Ian I Hutchinson and Tirza Klein and Ran Tur-Kaspa and Eytan Mor},
  journal={Transplantation},
  year={2006},
  volume={81 3},
  pages={392-7}
}
BACKGROUND Recurrent hepatitis C virus (HCV) infection is particularly aggressive in the post liver transplantation setting, with rapid progression of liver fibrosis. Platelet-derived growth factor (PDGF) is reportedly involved in the pathogenesis of liver fibrosis. The aim of this study was to evaluate the possible contribution of molecular variants of the PDGF-B gene to recurrent HCV infection after liver transplantation. METHODS DNA was extracted from peripheral blood mononuclear cells of… CONTINUE READING

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