Platelet-derived growth factor blocks the cell-cycle transition from the G0 to G1 phase in subcultured angiogenic endothelial cells in rat thoracic aorta.

Abstract

Platelet-derived growth factor (PDGF)-BB induces tube formation by the differentiating (tube-forming) endothelial cells (EC) of rat thoracic aorta, although PDGF-BB does not affect the proliferative EC (increasing the cell numbers) at the progression phase. These changes in the responses to PDGF-BB were due to the phenotype-dependent expression of PDGF beta… (More)

Topics

Cite this paper

@article{Kimura1997PlateletderivedGF, title={Platelet-derived growth factor blocks the cell-cycle transition from the G0 to G1 phase in subcultured angiogenic endothelial cells in rat thoracic aorta.}, author={Ikuo Kimura and Hiroshi Tsuneki and Michio Okabe and Masashi Ogasawara}, journal={Japanese journal of pharmacology}, year={1997}, volume={74 4}, pages={303-11} }