Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly

@inproceedings{Bloomekatz2017PlateletderivedGF,
  title={Platelet-derived growth factor (PDGF) signaling directs cardiomyocyte movement toward the midline during heart tube assembly},
  author={Joshua Bloomekatz and Reena Singh and Owen Wj Prall and Ariel C Dunn and Megan E Vaughan and Chin-San Loo and Richard P. Harvey and Deborah Yelon},
  booktitle={eLife},
  year={2017}
}
Communication between neighboring tissues plays a central role in guiding organ morphogenesis. During heart tube assembly, interactions with the adjacent endoderm control the medial movement of cardiomyocytes, a process referred to as cardiac fusion. However, the molecular underpinnings of this endodermal-myocardial relationship remain unclear. Here, we… CONTINUE READING